Effects of NAD+ on COVID-19

Effects of NAD+ on Covid-19

When your COVID-19 symptoms are at their worst, you’re probably just thinking of the basics. Rest, hydrate, and watch for further worsening symptoms. 

When people are sick, they often have low energy and appetite levels, which can lead to less liquid consumption and dehydration. What better time to receive and IV Infusion? With 100% of all vitamins and fluids entering into your system you’re accelerating your recovery process by instantly hydrating your body. 

In a recent study conducted by scientists from Bahrain published a proposal in the Journal of Infection and Public Health where they elaborated on the influence of a molecule called nicotinamide adenine dinucleotide (NAD+) in modulating the immune response to COVID-19. In their proposal, the researchers state the COVID-19 infection can lead to depleted cellular NAD+ levels and that restoring NAD+ levels could decrease the severity of the body’s immune reaction to the infection to improve the condition of COVID-19 patients. They believe that understanding the immune response mechanisms in SARS-CoV-2 will make the development of therapeutic options for the infection possible. 

Research indicates that alterations in immune responses accompany aging, including a reduced ability of the immune system to protect against infectious diseases and the reduced efficacy of vaccines in older adult populations. Differences at the DNA level exist between older and younger people that may influence the immune response, namely the length of telomeres, which are the ends of chromosomes . As people age, their telomeres become shorter due to the cell’s inability to fully replicate the ends of chromosomes during cell divisions when cells proliferate. NAD+-dependent enzymes called sirtuins modulate telomere length, and decreased NAD+ levels affect sirtuin activity and are associated with short telomeres that induce cell death.

Evidence that backs NAD+ treatments for COVID-19 patients:

  • The severity and outcome of COVID-19 largely depends on the patient’s age. Over 80% of hospitalized COVID-19 patients are over 65 years of age and have a 23-fold greater risk of death.
  • COVID-19 patients most commonly present with fever, cough, and dyspnea. Particularly in those over 65, however, symptoms can progress to pneumonia, cytokine release syndrome, multiple organ failures, and death.
  • The molecular differences between the young, middle-aged, and elderly may determine whether COVID-19 is a mild or life-threatening illness.
  • As we age, our immune system tends to recognize and respond to pathogens more slowly and to be overwhelmed by chronic inflammation (inflammaging).
  • A slower immune system gives the coronavirus time to replicate and cause more serious disease.
  • NAD is essential to many cell functions, including numerous aspects of stress resistance and pathogen defense.
  • NAD levels naturally decline as we age.
  • There is growing evidence that lower NAD+ levels in the lung and vascular endothelium contribute to poor COVID-19 outcomes.
  • NAD “boosters” can help give the elderly a “younger” immune system, which would recognize, respond, and clear the coronavirus before it was likely to become life-threatening.


Do you have any questions or concerns regarding NAD+ or about receiving a NAD+ IV treatment? We’ve got you covered! Give us a call today (720) 263-6409 to get your questions answered and an IV scheduled today!

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